Committee for the Evolution of Oncology Practices


The Comité de l’évolution des pratiques en oncologie (CEPO) [committee for the evolution of oncology practices] was established in 2001 by the Conseil québécois de lutte contre le cancer [Quebec council for the fight against cancer] of the Ministère de la Santé et des Services sociaux (MSSS) [Ministry of Health and Social Services] and began its work in 2002. Following an ad hoc collaboration with the Conseil du médicament [drug products council] to assess the therapeutic value of new molecules, the CEPO has been an official participant in the evaluation of anti-cancer drugs since 2011. Given the similarity of their respective mandates, the CEPO finally joined INESSS in 2013.

Made up of hematologists and medical oncologists, surgeons, radiation oncologists and pharmacists, the CEPO relies on the best scientific data available and on the experience of clinicians to optimize and standardize oncological clinical practice in Québec and thus provide better care to patients throughout the province who have or are suspected of having cancer.

The principal mandates of the CEPO are as follows:

  • to prepare and adopt algorithms, notices and statements of practice concerning cancer treatments (radiation therapy, surgery, chemotherapy, targeted therapy, etc.) and concerning the investigation examinations related to this disease;
  • to collaborate in the assessment of anti-cancer drugs for purposes of registration on the lists of medications in collaboration with the Comité scientifique permanent de l’évaluation des médicaments aux fins d’inscription (CSEMI) [standing scientific committee on entry on the list of medications];
  • to keep up to date with the scientific literature.

The CEPO also pursues mandates with the Direction générale de cancérologie (DGC) [cancer treatment branch] that fall outside the authority of INESSS, participating as an external reader in the development of administration guides for various cancer treatment drugs, patient tip sheets and pre-formatted prescriptions in consultation with the Comité national de l’évolution de la pratique des soins pharmaceutiques [national committee on the evolution of pharmaceutical care practice], which is part of the cancer treatment branch of MSSS.

From the outset of its activities, the CEPO has taken part in the development of more than 45 notices and state of knowledge reviews requiring the involvement of over 200 clinicians from all regions of Québec. It has also implemented six treatment algorithms and participated in the validation of more than 250 updates and in the development of new chemotherapy administration guides and patient tip sheets. In addition, the CEPO has taken part in evaluating the therapeutic value of more than 100 new cancer treatments to determine whether they should be entered on Québec’s lists of medications. During these evaluations, the Committee has called on the expertise of more than 100 clinicians.


Dr Félix Couture, Hématologue et oncologue médical
Hôtel-Dieu de Québec (CHU de Québec - Université Laval)


Dr Ghislain Cournoyer, Hématologue et oncologue médical
Hôpital régional de Saint-Jérôme (CISSS des Laurentides)


Dr Jean-Sébastien Aucoin, Hématologue et oncologue médical
Centre hospitalier affilié universitaire régional (CIUSSS de la Mauricie-et-du-Centre-du-Québec)

M. Philippe Bouchard, Pharmacien
Hôpital Maisonneuve-Rosemont (CIUSSS de l'Est-de-l'Île-de­-Montréal)

Dr Alexis Bujold, Radio-oncologue
Hôpital Maisonneuve-Rosemont (CIUSSS de l'Est-de-l'Île­ de-Montréal)

Dr Normand Gervais, Chirurgien oncologue
Centre hospitalier régional du Grand-Portage (CISSS du Bas-Saint-Laurent, secteur Rivière-du-Loup)

Mme Marie-Pascale Guay, Pharmacienne
Hôpital général juif (CIUSSS du Centre-Ouest-de-l'Île­-de-Montréal)

Dr Bernard Lespérance, Hématologue et oncologue médical
Hôpital du Sacré-Cœur de Montréal (CIUSSS du Nord-de-l'île-de-Montréal)

Mme Nathalie Letarte, Pharmacienne
Centre hospitalier de l'Université de Montréal (CHUM), représentante du Programme de gestion thérapeutique des médicaments

Dr Ari Meguerditchian, Chirurgien oncologue
Hôpital Royal Victoria (CUSM)

Dr Jean-François Ouellet, Chirurgien oncologue
Hôtel-Dieu de Québec (CHU de Québec - Université Laval)

Dr Benoît Samson, Hématologue et oncologue médical
Hôpital Charles-Le Moyne (CISSS de la Montérégie-Centre)

Dr François Vincent, Radio-oncologue
Centre hospitalier affilié universitaire régional (CIUSSS de la Mauricie-et-du-Centre-du-Québec)

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